Long-range GABAergic neurons in the prefrontal cortex modulate behavior.

Autor:	Bravo-Rivera C; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Diehl MM; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Roman-Ortiz C; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Rodriguez-Romaguera J; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Rosas-Vidal LE; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Bravo-Rivera H; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Quiñones-Laracuente K; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Do-Monte FH; Department of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico fabriciodomonte@gmail.com.
Jazyk:	angličtina
Zdroj:	Journal of neurophysiology [J Neurophysiol] 2015 Sep; Vol. 114 (3), pp. 1357-9. Date of Electronic Publication: 2014 Dec 17.
DOI:	10.1152/jn.00861.2014
Abstrakt:	Cortical glutamatergic projections are extensively studied in behavioral neuroscience, whereas cortical GABAergic projections to downstream structures have been overlooked. A recent study by Lee and colleagues (Lee AT, Vogt D, Rubenstein JL, Sohal VS. J Neurosci 34: 11519-11525, 2014) used optogenetic and electrophysiological techniques to characterize a behavioral role for long-projecting GABAergic neurons in the medial prefrontal cortex. In this Neuro Forum, we discuss the potential implications of this study in several learning and memory models. (Copyright © 2015 the American Physiological Society.)
Databáze:	MEDLINE
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