Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations.

Autor:	Dias BP; Faculty of Veterinary Medicine, Sao Paulo State University, Araçatuba, SP, Brazil., Araújo MA; Faculty of Veterinary Medicine and Animal Science, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil., Deschk M; Faculty of Veterinary Medicine, UNESP, Araçatuba, SP, Brazil., Trein TA; Faculty of Veterinary Medicine, UNESP, Araçatuba, SP, Brazil., Pinheiro NC; Department of Clinical, Surgey and Animal Reproduction, Faculty of Veterinary Medicine, UNESP, Araçatuba, SP, Acquisition., Perri SH; Department of Support, Animal Production and Health, Faculty of Veterinary Medicine, UNESP, Araçatuba, SP, Brazil., Rodrigues CA; Department of Surgery and Anesthesiology, Faculty of Veterinary Medicine, UNESP, Botucatu, SP, Brazil., Santos PS; Department of Clinical, Surgery and Animal Reproduction, Faculty of Veterinary Medicine, UNESP, Araçatuba, SP, Brazil.
Jazyk:	angličtina
Zdroj:	Acta cirurgica brasileira [Acta Cir Bras] 2014 Dec; Vol. 29 (12), pp. 801-6.
DOI:	10.1590/S0102-86502014001900006
Abstrakt:	Purpose: To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy. Methods: Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery. Results: There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG. Conclusions: Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group.
Databáze:	MEDLINE
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