[Pulmonary function of children with acute leukemia in maintenance phase of chemotherapy].

Autor: de Macêdo TM; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brasil., Campos TF; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brasil., Mendes RE; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brasil., França DC; Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil., Chaves GS; Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil., de Mendonça KM; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brasil. Electronic address: kmorganna@ufrnet.br.
Jazyk: portugalština
Zdroj: Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo [Rev Paul Pediatr] 2014 Dec; Vol. 32 (4), pp. 320-5.
DOI: 10.1016/j.rpped.2014.06.005
Abstrakt: Objective: The aim of this study was to assess the pulmonary function of children with acute leukemia.
Methods: Cross-sectional observational analytical study that enrolled 34 children divided into groups A (17 with acute leukemia in the maintenance phase of chemotherapy) and B (17 healthy children). The groups were matched for sex, age and height. Spirometry was measured using a spirometer Microloop Viasys(®) in accordance with American Thoracic Society and European Respiratory Society guidelines. Maximal respiratory pressures were measured with an MVD300 digital manometer (Globalmed(®)). Maximal inspiratory pressures and maximal expiratory pressures were measured from residual volume and total lung capacity, respectively.
Results: Group A showed a significant decrease in maximal inspiratory pressures when compared to group B. No significant difference was found between the spirometric values of the two groups, nor was there any difference between maximal inspiratory pressure and maximal expiratory pressure values in group A compared to the lower limit values proposed as reference.
Conclusion: Children with acute leukemia, myeloid or lymphoid, during the maintenance phase of chemotherapy exhibited unchanged spirometric variables and maximal expiratory pressure; However, there was a decrease in inspiratory muscle strength.
(Copyright © 2014 Associação de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.)
Databáze: MEDLINE
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