Dysphonia as a sign of HPV laryngeal infection: a case report.

Autor: Longubuco CE, dos Reis HL; Ginecology and Obstetrics Outpatient Care, Federal University of Espírito Santo (UFES), Vitória, Brazil. dr.hbarroso@gmail.com., Cavalcante FS, de Pinho CR, Oliveira NS, Nicol AF, Zamolyi RQ, Ferreira Dde C
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2014 Dec 11; Vol. 7, pp. 898. Date of Electronic Publication: 2014 Dec 11.
DOI: 10.1186/1756-0500-7-898
Abstrakt: Background: Voice dysfunction or dysphonia may be associated with several clinical conditions. Among these, laryngeal human papillomavirus (HPV)-induced lesions should be considered as a possible causative factor. We report a case of dysphonia in a patient presenting with an HPV laryngeal lesion. We also discuss the clinical features of the disease, its histopathological findings, and treatment and rigorous follow-up.
Case Presentation: We report a case of laryngeal papilloma in a 29-year-old, Afro-descendant, male patient with dysphonia. He was a non-smoker and was not a drug user. Videolaryngostroboscopy revealed signs suggestive of pharyngolaryngeal reflux. The right vocal fold presented with a papillomatous aspect in the posterior third, which underwent excision. Histopathological examination showed a nodular lesion of the right vocal fold, conclusive of squamous papilloma with absence of malignancy.
Conclusion: Patients presenting with persistent voice dysfunction or dysphonia should be investigated for possible laryngeal HPV infection. Diagnostic confirmation by HPV genotyping is important for follow-up of potential recurrence.
Databáze: MEDLINE