| Autor: |
Dupont A; a Institute of Medical Microbiology and Hospital Epidemiology; Hannover Medical School ; Hannover , Germany., Heinbockel L, Brandenburg K, Hornef MW |
| Jazyk: |
angličtina |
| Zdroj: |
Gut microbes [Gut Microbes] 2014; Vol. 5 (6), pp. 761-5. |
| DOI: |
10.4161/19490976.2014.972238 |
| Abstrakt: |
The intestinal mucosa squares the circle by allowing efficient nutrient absorption while generating a firm barrier toward the enteric microbiota, enteropathogenic microorganisms and high luminal concentrations of potent immunostimulatory molecules. The mucus layer together with local antimicrobial and anti-inflammatory peptides significantly contribute to this ability. Here we summarize the recent progress made to better understand the critical importance of this dynamic, complex and highly structured anti-inflammatory and antimicrobial barrier. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
