Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids.

Autor: Allen SF; Department of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA. Electronic address: scal@med.umich.edu., Godley RW; Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA., Evron JM; Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA., Heider A; Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan, USA., Nicklas JM; Department of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA., Thomas MP; Department of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.
Jazyk: angličtina
Zdroj: The Canadian journal of cardiology [Can J Cardiol] 2014 Dec; Vol. 30 (12), pp. 1732.e13-5. Date of Electronic Publication: 2014 Aug 28.
DOI: 10.1016/j.cjca.2014.08.025
Abstrakt: A previously healthy 48-year-old woman was evaluated for lightheadedness and chest heaviness 2 weeks after starting the herbal supplement Garcinia cambogia. She was found to be hypotensive and had an elevated serum troponin level. The patient had a progressive clinical decline, ultimately experiencing fulminant heart failure and sustained ventricular arrhythmias, which required extracorporeal membrane oxygenation support. Endomyocardial biopsy results were consistent with acute necrotizing eosinophilic myocarditis (ANEM). High-dose corticosteroids were initiated promptly and her condition rapidly improved, with almost complete cardiac recovery 1 week later. In conclusion, we have described a case of ANEM associated with the use of Garcinia cambogia extract.
(Copyright © 2014 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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