Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma: two case reports and literature review.
| Autor: | Orlandi E; Units of Radiotherapy 2, Fondazione IRCCS Istituto Nazionale Tumori, Via Giacomo Venezian, 1, 20133 Milan, Italy., Takanen S, Giandini T, Iannacone E, Fontanella W, Locati L, Carrara M, Bossi P, Bergamini C, Granata R, Tombolini V, Ibba T, Licitra L, Pignoli E, Fallai C |
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| Jazyk: | angličtina |
| Zdroj: | Future oncology (London, England) [Future Oncol] 2014 Nov; Vol. 10 (14), pp. 2111-20. |
| DOI: | 10.2217/fon.14.148 |
| Abstrakt: | Aims: To evaluate technical issues and clinical outcomes after postoperative volumetric-modulated arc therapy (VMAT) in two cases of malignant lacrimal gland cancer. Patients & Methods: Patients were treated by postoperative VMAT and post-treatment clinical outcomes were followed-up to 18 months. Results: Dosimetric results were acceptable and acute toxicity was manageable in both patients. No evidence of disease was found at latest follow-up. One patient underwent corneal transplant for central corneal ulceration, experiencing reduction of visual acuity. Conclusion: Postoperative VMAT for treatment of lacrimal gland tumors offers improved outcome, with manageable side effects. In the context of photon beam radiotherapy, VMAT emerged as a valuable treatment option for these malignant tumors. |
| Databáze: | MEDLINE |
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