Potential benefits of potassium deposition with periodic fluid redistribution using periodic head down tilt during diminished muscular activity.

Autor:	Federenko YF, Merkov PL, Yaroshenko YN, Denogratov SK, Charapakhin KP, Neofitov NH
Jazyk:	angličtina
Zdroj:	Indian journal of physiology and pharmacology [Indian J Physiol Pharmacol] 2014 Jan-Mar; Vol. 58 (1), pp. 30-8.
Abstrakt:	Objective: Fluid redistribution (FR) is an important cornerstone in treating diseases. Findings of FR with periodic head down tilt (PHDT) had sparked renewed interest in treating electrolyte disturbances. Therefore this study aimed to determine the potential benefits of potassium (K+) deposition with periodic FR by PHDT during diminished muscular activity (hypokinesia; HK). Methods: Studies were conducted on 40-male volunteers. They were equally divided into 4-groups: active control subjects (ACS), hypokinetic subjects (HKS), periodic fluid redistribution control subjects (PFRCS) and periodic fluid redistribution hypokinetic subjects (PFRHS). Results: Muscle K+ increased (p < 0.05) and plasma K+ level and K+ losses decreased (p < 0.05) in the PFRHS group compared to the HKS group. By contrast in the HKS group muscle K+ reduced (p < 0.05) and plasma K+ level and K+ losses increased (p < 0.05) compared to pre-experimental period levels and the values of the other groups. In the PFRCS group the muscle K+, plasma K+ concentration and K+ losses were affected much less than in the PFRHS group. Conclusion: The current study shows that periodic-applied fluid volume addition into the body's regional areas by PHDT increases muscle K+ content and decrease K+ losses suggesting potential benefits of K+ deposition during diminished muscular activity.
Databáze:	MEDLINE
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