Aciclovir-induced neurotoxicity: Utility of CSF and serum CMMG levels in diagnosis.

Autor: Berry L; Department of Infectious Diseases, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, United Kingdom(1). Electronic address: Louise.berry@nuh.nhs.uk., Venkatesan P; Department of Infectious Diseases, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, United Kingdom(1).
Jazyk: angličtina
Zdroj: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [J Clin Virol] 2014 Dec; Vol. 61 (4), pp. 608-10. Date of Electronic Publication: 2014 Sep 17.
DOI: 10.1016/j.jcv.2014.09.001
Abstrakt: Aciclovir is an anti-viral frequently used for herpes virus infections. Neurotoxicity and nephrotoxicity are uncommon but serious side effects of aciclovir treatment. This case illustrates how aciclovir induced neurotoxicity can present and how it can be diagnosed using quantitative assays of aciclovir and its metabolite in the CSF and serum.
(Copyright © 2014 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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