A pilot study on total, corneal, and internal aberrations in insulin-dependent and non-insulin-dependent diabetes mellitus patients.

Autor: Calvo-Maroto AM; Optometry Research Group, Department of Optics, University of Valencia, Dr. Moliner 50, 46100, Burjassot, Valencia, Spain., Pérez-Cambrodí RJ, García-Lázaro S, Albarrán-Diego C, Cerviño A
Jazyk: angličtina
Zdroj: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2015 Apr; Vol. 253 (4), pp. 645-53. Date of Electronic Publication: 2014 Nov 25.
DOI: 10.1007/s00417-014-2864-3
Abstrakt: Purpose: To explore the distribution of total, corneal, and internal higher-order aberrations (HOAs) in both insulin-dependent (IDDM) and non-insulin-dependent (NIDDM) diabetic patients.
Methods: Pilot study including seven patients with IDDM (14 eyes) and 11 patients with NIDDM (22 eyes). Ocular HOAs were examined using ray tracing aberrometry (i-Trace, Tracey Technologies Corp., Houston, TX) and the measurements of anterior segment using Scheimpflug imaging (Pentacam, Oculus Inc. Germany).
Results: Total HOAs was slightly higher in IDDM (0.634 ± 0.228 μm, 95% IC ± 0.131) than in NIDDM patients (0.527 ± 0.245 μm, 95% IC ± 0.108) (p = 0.267). The greatest contributor for total ocular HOAs was internal vertical coma (Z3 (- 1)) for both diabetic groups. In NIDDM, age and central corneal thickness (CCT) were correlated with total HOAs (p < 0.001, p = 0.0180 respectively); however, anterior chamber volume (ACV) was inversely correlated with total HOAs (p = 0.019). In IDDM, total HOAs were correlated with posterior asphericity (Q) (p = 0.002) and inversely correlated with ageing (p = 0.013).
Conclusions: Diabetic patients showed high values of total and internal vertical coma (Z3 (- 1)). There might be a role for optical quality measurements in monitoring changes due to DM.
Databáze: MEDLINE
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