Study of Auditory, Visual Reaction Time and Glycemic Control (HBA1C) in Chronic Type II Diabetes Mellitus.

Autor: M M; Associate Professor, Department of Physiology, Chennai Medical College Hospital & Research Centre , Trichy, Tamilnadu, India ., Sembian U; Associate Professor, Department of Anatomy, Chennai Medical College Hospital & Research Centre , Trichy, Tamilnadu, India ., Babitha; Assistant Professor, Department of Physiology, Vinayaka Missions University , Salem, Pondicherry, India ., N E; Reader, Department of Physiology, Madurai Medical College , Madurai, India ., K M; Reader, Department of Physiology, Madurai Medical College , Madurai, India .
Jazyk: angličtina
Zdroj: Journal of clinical and diagnostic research : JCDR [J Clin Diagn Res] 2014 Sep; Vol. 8 (9), pp. BC11-3. Date of Electronic Publication: 2014 Sep 20.
DOI: 10.7860/JCDR/2014/8906.4865
Abstrakt: Background: Diabetes mellitus is a disease of insulin deficiencyleads to micro and macro vascular disorder. Neuropathy is one of the major complication of chronic uncontrolled Diabetes affecting the Reaction time.
Objectives: To study the correlation between the glycosylated HbA1C and Auditory, visual Reaction time in chronic Type II diabetes (40-60y) of on oral hypoglycemic drugs of>10 y duration in two groups (n-100 in each group , both Males & females) and compared within the study groups and also with the age matched control group (100).
Materials and Methods: HbA1C-Glycosylated HbA1C was measured by Particle enhanced immunoturbidimetric test method. Auditory and visual reaction time (ART, VRT) were measured by PC 1000 Reaction timer for control & study groups i.e. Group-I - Chronic Type II DM for >10 y with HbA1c < 7.0, and Group II - chronic Type-IIDM for >10 y with HbA1c > 7.0 ie impaired glycemic control. Exclusion Criteria- Subjects with Auditory and visual disturbances, alcoholism and smoking. Statistical Analysis - One-way ANOVA. Using SPSS 21 software.
Result: Both the groups had prolonged ART and VRT than controls. Among the study group, G-II (DM with HbA1C >7) had increased Auditory & Visual Reaction time than Group I which is statistically significant p-value <0.05.
Conclusion: Impairment of sensory motor function of peripheral nervous system is more in chronic diabetic with less glycemic control ie., HbA1C>7 who have shown increased Auditory and Visual Reaction time than chronic DM with HbA1C<7.Severity of Peripheral neuropathy in Type II Diabetics could be due to elevated HbA1C.
Databáze: MEDLINE
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