More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review.
| Autor: | Badulescu F; Department of Oncology, Universitatea de Medicina si Farmacie, Craiova, Romania., Badulescu A; Department of Surgery, Universitatea Titu Maiorescu, Bucuresti, Romania., Paul D; Monter Cancer Center, North Shore LIJ Cancer Institute, Lake Success, NY, USA., Popescu CF; Department of Pathology, Spitalul Universitar Clinic de Urgenta, Craiova, Romania., Florescu C; Department of Cardiology, Universitatea de Medicina si Farmacie, Craiova, Romania. |
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| Jazyk: | angličtina |
| Zdroj: | OncoTargets and therapy [Onco Targets Ther] 2014 Oct 17; Vol. 7, pp. 1911-7. Date of Electronic Publication: 2014 Oct 17 (Print Publication: 2014). |
| DOI: | 10.2147/OTT.S69343 |
| Abstrakt: | The main concern of long-term use of trastuzumab remains its association with potential cardiac side effects. Although these side effects are real, they are probably overemphasized. We report the case of a woman with metastatic breast cancer, who is currently in complete remission, and who received trastuzumab continuously for more than 9 years, without any significant cardiac toxicity. |
| Databáze: | MEDLINE |
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