Frequency and molecular types of deletional alpha-thalassemia in Egypt.

Autor: Novelletto A; Dipartimento di Biologia, Università Tor Vergata, La Romanina, Rome, Italy., Hafez M, Di Rienzo A, Felicetti L, Deidda G, el Morsi Z, al-Tonbary Y, el-Ziny M, Abd-el-Gelil N, Terrenato L
Jazyk: angličtina
Zdroj: Human genetics [Hum Genet] 1989 Feb; Vol. 81 (3), pp. 211-3.
DOI: 10.1007/BF00278990
Abstrakt: The frequency of deletional alpha-thalassemia in the Egyptian population was estimated at 0.08 by DNA analysis of a newborn random sample. No alpha 0 determinants were found. The most frequent alpha+ determinant was the -alpha 3.7 type I in association with the medium allele at inter-zeta HVR. The -alpha 4.2 and alpha alpha alpha anti 3.7 arrangements were found at very low frequencies.
Databáze: MEDLINE