Newborns with congenital heart diseases: epidemiological data from a single reference center in Brazil.

Autor: Silva KP; Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil., Rocha LA; Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil., Leslie AT; Discipline of Neonatology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil., Guinsburg R; Discipline of Neonatology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil., Silva CM; Discipline of Cardiology, Department of Clinics, São Paulo Federal University (UNIFESP), São Paulo-SP, Brazil., Nardozza LM; Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil., Moron AF; Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil., Araujo Júnior E; Fetal Cardiology Unit, Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo-SP, Brazil.
Jazyk: angličtina
Zdroj: Journal of prenatal medicine [J Prenat Med] 2014 Jan-Mar; Vol. 8 (1-2), pp. 11-6.
Abstrakt: Objective: to describe the epidemiological data of the population born with the diagnosis of Congenital Heart Disease (CHD); to compare diagnoses made using fetal echocardiography with the findings from postnatal echocardiography or anatomopathological examination of the heart; and to evaluate mortality among newborns that underwent surgical treatment.
Methods: this was a cohort study with information gathered from the medical records of the pregnant women and their newborns diagnosed with CHD during the fetal or postnatal periods, between January 2008 and December 2012. Means, standard deviations and maximum and minimum values were calculated for the quantitative variables. Relative and absolute values were calculated for the qualitative variables. The heart malformations were categorized in four groups: complex lesions, significant lesions, minor lesions and others.
Results: we detected postnatal incidence of CHD of 1.9% at our service. The mean maternal age was 28.3 years and 10 (21.3%) of the pregnant women were ≥ 35 years old. The mean gestational age at the time of performing the fetal echocardiogram was 27.8 weeks. Mean gestational age at delivery was 38 weeks, and the mean weight of the newborns was 2,644.5 grams. Regarding the diagnosis of CHD, there were: 23 complex lesions (39%); 15 significant lesions (26%); 10 minor lesions (17%); 4 other lesions (7%) and 6 normal anatomies (10%). The diagnosis of CHD made on the fetus and postnatally coincided in 77.6% of the cases. A total of 27 patients (60%) underwent surgery, and the outcome was neonatal death in five cases.
Conclusion: we detected postnatal incidence of CHD of 1.9%, and it was more common among older pregnant women and with late detection in the intrauterine period. Complex heart diseases predominated, thus making it difficult to have a good result regarding neonatal mortality rates.
Databáze: MEDLINE
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