| Autor: |
Tokareva OG, Ivanov AV, Danilova NV, Gorodetskaia EA, Mal'kov PG, Gaĭfullin NM, Kalenikova EI, Medvedev OS |
| Jazyk: |
ruština |
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2014; Vol. 77 (7), pp. 8-10. |
| Abstrakt: |
The influence of coenzyme Q10 (CoQ10) on early ischemic deterioration was studied on Wistar rats with experimental myocardial infarction. CoQ10 (30 mg/kg) was injected intravenously 10 min after coronary artery occlusion, and morphometric analysis was performed for 72 h after the onset of ischemia. CoQ10-treated rats had restricted total myocardial damage (by 52%), including areas of necrosis (by 84%) and areas of cellular inflammatory infiltration (by 38%) as compared to saline-treated rats (p < 0.001). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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