| Autor: |
Khomenko RM, Gruzov MA, Shliakhovenko VS, Lukinov DI, Komissarenko SV, Zak KP |
| Jazyk: |
ruština |
| Zdroj: |
Fiziologicheskii zhurnal [Fiziol Zh (1978)] 1989 Sep-Oct; Vol. 35 (5), pp. 31-7. |
| Abstrakt: |
The flowing cytofluorometric and electron microscopic methods have been used to study the content and ultrastructure of blood CD4 lymphocytes in healthy and type I diabetic patients. Analysis of submicroscopic structure of the lymphocytes expressing CD4 antigen has revealed its morphological heterogeneity. It has permitted distinguishing four groups of cells. A decrease of the content of CD4+ lymphocytes at the expense of the first group cells and relative increase in the number of the fourth-group cells are observed in the majority of diabetic patients. The availability of parallel-tubular structures in granules forming clusters and first-group lymphocytes, an increase in the number and size of granules of the fourth-group are the most typical changes of ultrastructural characteristics. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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