Seroprevalence of Toxocara spp. in children with atopy.

Autor:	Grama DF; Instituto de Ciências Biomédicas, Laboratório de Parasitologia, Universidade Federal de Uberlândia, Minas Gerais, Brazil., Lescano SZ; Instituto de Medicina Tropical de São Paulo (USP), Laboratório de Helmintologia, São Paulo, Brazil., Pereira Mota KC; Instituto de Ciências Biomédicas, Laboratório de Parasitologia, Universidade Federal de Uberlândia, Minas Gerais, Brazil., dos Anjos Pultz B; Instituto de Ciências Biomédicas, Laboratório de Parasitologia, Universidade Federal de Uberlândia, Minas Gerais, Brazil., Miranda JS; Instituto de Ciências Biomédicas, Laboratório de Parasitologia, Universidade Federal de Uberlândia, Minas Gerais, Brazil., Silva Segundo GR; Pediatric allergist, Ambulatório de Pediatria, Hospital de Clínicas da Universidade Federal de Uberlândia, Minas Gerais, Brazil., Taketomi EA; Instituto de Ciências Biomédicas, Laboratório de Alergia e Imunologia Clínica, Universidade Federal de Uberlândia, Minas Gerais, Brazil., Fernandes KP; Pediatric allergist, Ambulatório de Pediatria, Hospital de Clínicas da Universidade Federal de Uberlândia, Minas Gerais, Brazil., Limongi JE; Instituto de Ciências Biomédicas, Laboratório de Parasitologia, Universidade Federal de Uberlândia, Minas Gerais, Brazil., de Paula FM; Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Chieffi PP; Instituto de Medicina Tropical de São Paulo (USP), Laboratório de Helmintologia, São Paulo, Brazil., Cury MC; Instituto de Ciências Biomédicas, Laboratório de Parasitologia, Universidade Federal de Uberlândia, Minas Gerais, Brazil cury@umuarama.ufu.br.
Jazyk:	angličtina
Zdroj:	Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2014 Dec; Vol. 108 (12), pp. 797-803. Date of Electronic Publication: 2014 Oct 13.
DOI:	10.1093/trstmh/tru165
Abstrakt:	Background: Epidemiological studies around the world suggest that infection with Toxocara spp. can contribute to the development or worsening of atopic diseases, especially in children. This study investigated the seroprevalence of toxocariasis in atopic children treated at the pediatric clinic of the Federal University of Uberlândia Clinical Hospital, identifying possible relationships with risk factors. Methods: The study was conducted between November 2011 and March 2013. Blood samples were collected from 173 children aged 6 to 15 years, who were first subjected to clinical exams and then to a skin-prick test to determine the presence or absence of atopy. Risk factors for toxocariasis were analyzed based on a questionnaire. Serum samples were tested for the presence of IgG antibodies to Toxocara spp. by means of enzyme-linked immunosorbent assay. Results: The seroprevalence of Toxocara spp. was 19.6% (24/122) in atopic children and 15% (8/51) in non-atopic children, with no statistical difference. No significant association was found between infection and possible risk factors in atopic and non-atopic children. Conclusions: Although no statistical association was found between human toxocariasis and atopy, this study revealed a high seroprevalence of Toxocara spp. in children that may indicate environmental contamination with the parasite's eggs in the area where these children live. (© The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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