[Some indices of trace elements and antioxidant status in rats under chromic intoxication].

Autor: Mikhailova IV, Chesnokova LA, Sharapova NV, Smolyagin AI, Krasikov SI
Jazyk: ruština
Zdroj: Gigiena i sanitariia [Gig Sanit] 2014 May-Jun (3), pp. 71-4.
Abstrakt: There was investigated the effect of chronic Cr (VI) on the content of chromium, iron, copper; zinc, nickel in the blood of rats and activity of antioxidant enzymes of erythrocytes in Wistar rats. The chromium concentration has been shown to increase multifold while the level of other metal is more or less declining. Also it was found a decrease in the activity of such antioxidant enzymes as superoxide dismutase, catalase, and the activation of the processes of free radical oxidation. Thus, it can be assumed that the effect of Cr (VI) is implemented via an imbalance of trace elements and the activation of the processes of free radical oxidation.
Databáze: MEDLINE