| Autor: |
Luderer MR; Department of Natural Science, Mathematics, and Engineering, University of Pittsburgh at Greensburg , Greensburg, Pennsylvania 15601, United States., Mealy MJ, Bailey WF |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of organic chemistry [J Org Chem] 2014 Nov 07; Vol. 79 (21), pp. 10722-6. Date of Electronic Publication: 2014 Oct 23. |
| DOI: |
10.1021/jo502139m |
| Abstrakt: |
Concise syntheses of the sesquiterpenes (R)-(+)-cuparene and (R)-(+)-herbertene by asymmetric cyclization of achiral olefinic alkyllithium precursors in the presence of (-)-sparteine are reported. The quaternary stereogenic center in each product is set at the final step of the synthesis by enantioselective (er = 61:39) 5-exo ring closure. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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