| Autor: |
Chimishkian KL, Baryshnikov AIu, Ovumian GSh, Kostrykina VN, Karpov IA, Buntsevich AM, Slavina EG, Udalov GA, Kadagidze ZG |
| Jazyk: |
ruština |
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1989 Jul; Vol. 108 (7), pp. 83-5. |
| Abstrakt: |
The data on the application of monoclonal antibodies (ICO-10) and rabbit complement for working the conditions of allogeneic bone marrow transplantation are presented in the paper. The treatment with monoclonal antibodies and bone marrow complement from BALB/c mice for 2 times prevented the development of transplant versus host reaction and completely protected lethally irradiated (CBA X X C57B1/6)FI mice-recipients from death. Thymus atrophy and the absence of T-cells in the peripheral blood was observed in these mice. The erythrocytes had markers characteristic of BALB/c and (CBA X C57B1/6)FI mice. Mouse splenocytes did not respond to the cells of donors and recipients in mixed lymphocyte culture reaction. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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