Body mass index as a determinant of carotid intima-media thickness in Nigerian adults with primary hypertension.

Autor: Eric OU, Atinuke MA; Department of Radiology, University College Hospital, Ibadan, Oyo State, Nigeria., Abiodun OA, Ademola JA
Jazyk: angličtina
Zdroj: Annals of African medicine [Ann Afr Med] 2014 Oct-Dec; Vol. 13 (4), pp. 151-6.
DOI: 10.4103/1596-3519.142274
Abstrakt: Background: Long standing hypertension may result in thickening of arterial walls and is reportedly strongly correlated with body mass index (BMI). B-mode ultrasound is a reproducible method for evaluating adaptive vascular changes. The aim of this study is to determine the relationship between body mass index and ultrasound measured carotid intima-media thickness (CIMT) among adults with primary hypertension.
Materials and Methods: One hundred and twenty adults of both genders diagnosed with primary hypertension at the University College Hospital (UCH), Ibadan underwent B-mode ultrasound evaluation of the walls of the common and extracranial internal carotid arteries bilaterally. Participants' height and weight were measured and body mass index (BMI) was calculated.
Results: Study population had gender distribution of 50 (41.7%) and 70 (58.3%) for males and females, respectively; and a mean age of 50.61 ΁ 10.94 years. Mean height, weight, and BMI were 1.66 m, 69.36 kg, and 24.92 kg/m 2 for male subjects and 1.59 m, 65.6 kg, and 25.6 kg/m 2 for female subjects, respectively. Normal/underweight and overweight/obese male participants had mean CIMT of 0.744 and 0.820 mm (P < 0.05) on the right side of the neck and 0.740 and 0.816 mm (P < 0.05) on the left side, respectively. However, female participants showed no statistically significant variation in CIMT values for both BMI groups.
Conclusion: B-mode ultrasound demonstrates statistically significant variation in CIMT values between normal/underweight and overweight/obese male adults diagnosed with primary hypertension.
Databáze: MEDLINE
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