| Autor: |
Liakhovs'ka NV, Kutsenko NL, Mykytiuk MV, Kaĭdashev IP |
| Jazyk: |
ukrajinština |
| Zdroj: |
Likars'ka sprava [Lik Sprava] 2014 Mar-Apr (3-4), pp. 26-30. |
| Abstrakt: |
Allergic diseases are among the most popular in the world. Scientific hypothesis formation and multifactorial pathogenesis of atopic asthma (AA) is constantly updated. Our purpose of this study was to investigate the relationship of humoral and cellular immunity with features clinical and anamnestic data in patients AA. Found that AA is genetically determined disorders, mainly transmitted through the maternal line, characterized polisensibilization, most of household allergens. AA is often associated with other allergic nosology (62.2%) and gastrointestinal diseases (44.4%). In the absence of clinical evidence of disease at CD4+/CD25+/Foxp3+, IgE and IL-4 in patients with AA is higher than in healthy individuals. When polyvalent allergy has been a significant increase in IgE (199.3 +/- 22.2) and IL-4 (79.2 +/- 16.5) and reduced expression of molecules CD4+/CD25+/Foxp3+ compared with sensitization to one or two allergens. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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