Are Hemoglobin-Based Oxygen Carriers Being Withheld Because of Regulatory Requirement for Equivalence to Packed Red Blood Cells?

Autor: Mackenzie CF; 1University of Maryland School of Medicine, Baltimore, MD; 2OPK Biotech LLC, Cambridge, MA; 3Inkosi Albert Luthuli Central Hospital and Nelson R. Mandela School of Medicine, Department of Anesthesia and Pain Management, Durban, South Africa; 4Milpark Clinic, Department of Surgery, Johannesburg, South Africa; 5Sunninghill Hospital, Department of Surgery, Johannesburg, South Africa; 6David Geffen School of Medicine, Department of Anesthsiology, University of California, Los Angeles, Los Angeles, CA; and 7Brown University School of Medicine, Department of Surgery, Providence, RI., Pitman AN, Hodgson RE, Sussman MJ, Levien LJ, Jahr JS, Greenburg AG
Jazyk: angličtina
Zdroj: American journal of therapeutics [Am J Ther] 2015 Jul-Aug; Vol. 22 (4), pp. e115-21.
DOI: 10.1097/MJT.0000000000000009
Databáze: MEDLINE