| Autor: |
Takahashi N; Department of Orthopaedic Surgery, Southern Tohoku General Hospital, Fukushima, Japan; Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan., Arai I, Kayama S, Ichiji K, Fukuda H, Handa J, Konno S |
| Jazyk: |
angličtina |
| Zdroj: |
Fukushima journal of medical science [Fukushima J Med Sci] 2014; Vol. 60 (2), pp. 175-80. Date of Electronic Publication: 2014 Oct 04. |
| DOI: |
10.5387/fms.2014-14 |
| Abstrakt: |
A 22-year-old woman presented with complaints of severe pain in a wide region of the thoracolumbar spine. She developed severe pain in the thoracolumbar spine region 2 months after her first delivery and was referred 1 month later. A lateral thoracic X-ray showed depressed degenerative vertebrae (T7, T9). One month after the initial examination, thoracic sagittal magnetic resonance imaging showed low intensity areas on T1-weighted imaging and iso-high intensity areas on T2-weighted imaging at T5, 7, 8, 9 and 11. Bone mineral density measured by ultrasound was low (%YAM 76%). The bone metabolic markers were high, suggesting accelerated osteoclast activity. These findings prompted a diagnosis of pregnancy-associated osteoporosis. She was asked to stop breastfeeding and to wear a lumbar brace, and treatment with nutritional calcium, activated vitamin D3, and risedronate sodium was started. Her low back pain almost disappeared after treatment. Bone metabolic markers showed normalization 8 months after the initial examination. Risedronate sodium was stopped 2 years and 2 months after the initial examination. Teriparatide treatment was started because her bone mineral density remained low; however, the osteoblast marker P1NP was not increased 5 months after the start of teriparatide treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
