[Glycine receptors in nervous tissue and their functional role].

Autor: Nikandrov VN, Balashevich TV
Jazyk: ruština
Zdroj: Biomeditsinskaia khimiia [Biomed Khim] 2014 Jul-Aug; Vol. 60 (4), pp. 403-15.
DOI: 10.18097/pbmc20146004403
Abstrakt: The literature data on glycine metabolism in neural tissue, mitochondrial Gly-cleaving system, Gly-catching system in neural and glial cells are summarized. The peculiarities of localization and distribution of specific glycine receptors and binding-sites in nervous tissue of mammals are described. Four types of glycine-binding receptors are described: own specific glycine receptor (Gly-R), ionotropic receptor, which binds N-methyl-D-aspartate selectively (NMDA-R), and ionotropic receptors of g-aminobutyrate (GABA A -R, GABA С -R). The features of glycine effects in neuroglial cultures are discussed.
Databáze: MEDLINE