Concordance between digital pathology and light microscopy in general surgical pathology: a pilot study of 100 cases.

Autor:	Houghton JP; Centre for Medical Education, Queen's University Belfast, Belfast, N. Ireland., Ervine AJ; Institute of Pathology, Belfast, N. Ireland., Kenny SL; Institute of Pathology, Belfast, N. Ireland., Kelly PJ; Institute of Pathology, Belfast, N. Ireland., Napier SS; Institute of Pathology, Belfast, N. Ireland., McCluggage WG; Institute of Pathology, Belfast, N. Ireland., Walsh MY; Institute of Pathology, Belfast, N. Ireland., Hamilton PW; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, N. Ireland.
Jazyk:	angličtina
Zdroj:	Journal of clinical pathology [J Clin Pathol] 2014 Dec; Vol. 67 (12), pp. 1052-5. Date of Electronic Publication: 2014 Sep 23.
DOI:	10.1136/jclinpath-2014-202491
Abstrakt:	Aim: (1) A pilot study to determine the accuracy of interpretation of whole slide digital images in a broad range of general histopathology cases of graded complexity. (2) To survey the participating histopathologists with regard to acceptability of digital pathology. Materials and Methods: Glass slides of 100 biopsies and minor resections were digitally scanned in their entirety, producing digital slides. These cases had been diagnosed by light microscopy at least 1 year previously and were subsequently reassessed by the original reporting pathologist (who was blinded to their original diagnosis) using digital pathology. The digital pathology-based diagnosis was compared with the original glass slide diagnosis and classified as concordant, slightly discordant (without clinical consequence) or discordant. The participants were surveyed at the end of the study. Results: There was concordance between the original light microscopy diagnosis and digital pathology-based diagnosis in 95 of the 100 cases while the remaining 5 cases showed only slight discordance (with no clinical consequence). None of the cases were categorised as discordant. Participants had mixed experiences using digital pathology technology. Conclusions: In the broad range of cases we examined, digital pathology is a safe and viable method of making a primary histopathological diagnosis. (Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.)
Databáze:	MEDLINE
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