Peripheral giant cell granulomas: a series of 279 cases.

Autor: Lester SR; Postgraduate Resident, Department of Periodontics, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA., Cordell KG; Associate Professor, Division of Oral and Maxillofacial Pathology, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA., Rosebush MS; Assistant Professor, Division of Oral and Maxillofacial Pathology, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA., Palaiologou AA; Associate Professor, Department of Periodontics, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA. Electronic address: Apalai@lsuhsc.edu., Maney P; Assistant Professor, Department of Periodontics, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA.
Jazyk: angličtina
Zdroj: Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2014 Oct; Vol. 118 (4), pp. 475-82. Date of Electronic Publication: 2014 Jul 05.
DOI: 10.1016/j.oooo.2014.06.004
Abstrakt: Objective: This study investigated the demographic, clinicopathologic, and histopathologic findings of lesions diagnosed as peripheral giant cell granuloma (PGCG) by the Louisiana State University Oral Pathology Biopsy Service from 1974 to 2011.
Study Design: Clinical, demographic, and histopathologic evaluation was completed for 279 cases. A follow-up questionnaire was mailed to all surgeons who performed these biopsies from 1990 to 2011.
Results: Of the 279 lesions, 58% occurred in the mandible, 44% occurred in the anterior portion of the arches, 83% were adjacent to teeth, 14% occurred in edentulous areas, and 2% were adjacent to implants. Average duration was 10.5 months, and the average size was 12.7 mm. The recurrence rate was 17.5%. Histopathologically, 78% of lesions extended to the base of the specimen, 50% exhibited ulceration, 41% contained calcifications, and 6% exhibited features overlapping with another pathologic entity.
Conclusions: PGCG is a well-defined pathologic entity among reactive gingival lesions. Recurrent lesions were more likely to contain calcifications.
(Copyright © 2014 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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