Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

Autor: Mendrone A Jr, Cerutti C Jr, Levi JE; Fundação Pró-Sangue, Hemocentro de São Paulo, São Paulo, Brazil. jelevi@prosangue.sp.gov.br., Boulos M, Sanchez MC, Malafronte Rdos S, Di Santi SM, Odone V Jr
Jazyk: angličtina
Zdroj: Malaria journal [Malar J] 2014 Aug 28; Vol. 13, pp. 336. Date of Electronic Publication: 2014 Aug 28.
DOI: 10.1186/1475-2875-13-336
Abstrakt: A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum, a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city.
Databáze: MEDLINE