Biocompatibility of Ricinus communis polymer with addition of calcium carbonate compared to titanium. Experimental study in guinea pigs.
| Autor: | Graça YL; Research Center, Denton Cooley Research Institute., Opolski AC, Barboza BE; Research Center, Denton Cooley Research Institute., Erbano BO; Research Center, Denton Cooley Research Institute., Mazzaro CC; Research Center, Denton Cooley Research Institute., Klostermann FC; Research Center, Denton Cooley Research Institute., Sucharski EE; Research Center, Denton Cooley Research Institute., Kubrusly LF; Hospital Vita, Instituto do Coração, Universidade Federal do Paraná, Curitiba, PR, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular [Rev Bras Cir Cardiovasc] 2014 Apr-Jun; Vol. 29 (2), pp. 272-8. |
| DOI: | 10.5935/1678-9741.20140030 |
| Abstrakt: | Objective: The aim of the present investigation was to determine whether the difference in inflammatory tissue reaction between the Riccinus communis (castor) polymer with calcium carbonate and the titanium implant is statistically significant. Methods: Thirty-two Cavia porcellus were allocated into four groups of eight animals each. We implanted the two types of materials in the retroperitoneal space of all the animals. They were euthanized at 7, 20, 30 and 40 days after surgery, and an histological study of the samples was conducted. Results: All implants showed characteristics of chronic inflammation regardless of the material and timepoint of evaluation. There was no statistically significant difference between Pm+CaCO3 and Ti with regard to the presence of granulation tissue, tissue congestion, histiocytes, lymphocytes, neutrophils, giant cells, and fibrosis (P> 0.05). Conclusion: The castor oil polymer plus calcium carbonate implant was not statistically different from the titanium implant regarding inflammatory tissue reaction. |
| Databáze: | MEDLINE |
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