Thoracic manifestations of connective tissue diseases.

Autor: Ruano CA; Department of Radiology, Hospital de Santo António dos Capuchos, Central Lisbon Hospital Centre, Lisbon, Portugal. Electronic address: carinaasr@gmail.com., Lucas RN; Department of Radiology, Hospital de Santo António dos Capuchos, Central Lisbon Hospital Centre, Lisbon, Portugal., Leal CI; Department of Radiology, Hospital de Santa Marta, Central Lisbon Hospital Centre, Lisbon, Portugal., Lourenço J; Department of Radiology, Hospital de Santo António dos Capuchos, Central Lisbon Hospital Centre, Lisbon, Portugal., Pinheiro S; Department of Internal Medicine, Hospital de Santo António dos Capuchos, Central Lisbon Hospital Centre, Lisbon, Portugal., Fernandes O; Department of Radiology, Hospital de Santa Marta, Central Lisbon Hospital Centre, Lisbon, Portugal., Figueiredo L; Department of Radiology, Hospital de Santa Marta, Central Lisbon Hospital Centre, Lisbon, Portugal.
Jazyk: angličtina
Zdroj: Current problems in diagnostic radiology [Curr Probl Diagn Radiol] 2015 Jan-Feb; Vol. 44 (1), pp. 47-59. Date of Electronic Publication: 2014 Aug 15.
DOI: 10.1067/j.cpradiol.2014.07.002
Abstrakt: Connective tissue diseases (CTDs) comprise several immunologic systemic disorders, each of which associated with a particular set of clinical manifestations and autoimmune profile. CTDs may cause numerous thoracic abnormalities, which vary in frequency and pattern according to the underlying disorder. The CTDs that most commonly involve the respiratory system are progressive systemic sclerosis, systemic lupus erythematosus, rheumatoid arthritis, Sjögren syndrome, polymyositis, dermatomyositis, and mixed connective tissue disease. Pulmonary abnormalities in this group of patients may result from CTD-related lung disease or treatment complications, namely drug toxicity and opportunistic infections. The most important thoracic manifestations of CTDs are interstitial lung disease and pulmonary arterial hypertension, with nonspecific interstitial pneumonia being the most common pattern of interstitial lung disease. High-resolution computed tomography is a valuable tool in the initial evaluation and follow-up of patients with CTDs. As such, general knowledge of the most common high-resolution computed tomographic features of CTD-related lung disease allows the radiologist to contribute to better patient management.
(Copyright © 2014 Mosby, Inc. All rights reserved.)
Databáze: MEDLINE
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