Sensitive determination of carbidopa through the electrochemiluminescence of luminol at graphene-modified electrodes.

Autor: Hosseini M; Department of Life Science Engineering, University of Tehran, Tehran, Iran., Mirzanasiri N, Rezapour M, Sheikhha MH, Faridbod F, Norouzi P, Ganjali MR
Jazyk: angličtina
Zdroj: Luminescence : the journal of biological and chemical luminescence [Luminescence] 2015 Jun; Vol. 30 (4), pp. 376-81. Date of Electronic Publication: 2014 Aug 13.
DOI: 10.1002/bio.2742
Abstrakt: Using the concept of electrogenerated chemiluminescence (ECL), a sensitive analytical method for the determination of carbidopa is described. Electro-oxidation of carbidopa on the surface of a graphene oxide (GO)-modified gold electrode (GE) leads to enhancement of the weak emission of oxidized luminol. Under optimum experimental conditions, the ECL signal increases linearly with increasing carbidopa concentrations over a range of 1.0 × 10(-9) -1.7 × 10(-7)  M, with a detection limit of 7.4 × 10(-10)  M. The proposed ECL method was successfully used for the determination of carbidopa in urine samples.
(Copyright © 2014 John Wiley & Sons, Ltd.)
Databáze: MEDLINE
Externí odkaz: