Left atrial volume index and prediction of events in acute coronary syndrome: Solar Registry.

Autor:	Secundo Junior JA; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Santos MA; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Faro GB; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Soares CB; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Silva AM, Secundo PF; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Teixeira CK; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Oliveira JL; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Barreto Filho JA; Universidade Federal de Sergipe, Aracaju, SE, Brazil., Sousa AC; Universidade Federal de Sergipe, Aracaju, SE, Brazil.
Jazyk:	English; Portuguese
Zdroj:	Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2014 Oct; Vol. 103 (4), pp. 282-91. Date of Electronic Publication: 2014 Aug 13.
DOI:	10.5935/abc.20140122
Abstrakt:	Background: According to some international studies, patients with acute coronary syndrome (ACS) and increased left atrial volume index (LAVI) have worse long-term prognosis. However, national Brazilian studies confirming this prediction are still lacking. Objective: To evaluate LAVI as a predictor of major cardiovascular events (MCE) in patients with ACS during a 365-day follow-up. Methods: Prospective cohort of 171 patients diagnosed with ACS whose LAVI was calculated within 48 hours after hospital admission. According to LAVI, two groups were categorized: normal LAVI (≤ 32 mL/m2) and increased LAVI (> 32 mL/m2). Both groups were compared regarding clinical and echocardiographic characteristics, in- and out-of-hospital outcomes, and occurrence of ECM in up to 365 days. Results: Increased LAVI was observed in 78 patients (45%), and was associated with older age, higher body mass index, hypertension, history of myocardial infarction and previous angioplasty, and lower creatinine clearance and ejection fraction. During hospitalization, acute pulmonary edema was more frequent in patients with increased LAVI (14.1% vs. 4.3%, p = 0.024). After discharge, the occurrence of combined outcome for MCE was higher (p = 0.001) in the group with increased LAVI (26%) as compared to the normal LAVI group (7%) [RR (95% CI) = 3.46 (1.54-7.73) vs. 0.80 (0.69-0.92)]. After Cox regression, increased LAVI increased the probability of MCE (HR = 3.08, 95% CI = 1.28-7.40, p = 0.012). Conclusion: Increased LAVI is an important predictor of MCE in a one-year follow-up.
Databáze:	MEDLINE
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