| Autor: |
Lygo B; School of Chemistry, The University of Nottingham, University Park, Nottingham, NG7 2RD, UK., Palframan MJ, Pattenden G |
| Jazyk: |
angličtina |
| Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2014 Oct 07; Vol. 12 (37), pp. 7270-8. |
| DOI: |
10.1039/c4ob00734d |
| Abstrakt: |
DFT calculations probing potential (4 + 2) and (4 + 3) cycloaddition pathways leading to the polycyclic ring systems found in the coral secondary metabolites plumarellide, mandapamate and rameswaralide are described. Formation of plumarellide and mandapamate via stepwise intramolecular cycloaddition of a furanoxonium ion onto a 1,3-diene is shown to be viable. The calculations also predict the outcome of related cyclisations involving model systems. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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