Auditory p300 event-related potentials in children with Sydenham's chorea.
| Autor: | Ozdemir HH; Dicle University, Diyarbak?r, Turkey., Demiroren K; Van Yüzüncü Y?l Universtity, Van, Turkey., Demir CF; Firat University, Elaz??, Turkey., Serin MH; Firat University, Elaz??, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2014 Aug; Vol. 72 (8), pp. 603-8. |
| DOI: | 10.1590/0004-282x20140099 |
| Abstrakt: | Unlabelled: P300 event-related potentials (ERPs), objective measures related to cognitive processing, have not been studied in Sydenham's chorea (SC) patients. Purpose: To assess cognitive impairment with P300 ERPs. Method: Seventeen patients with SC and 20 unaffected healthy children were included. Stanford-Binet test was used for psychometric assessment, and odd-ball paradigm was used for auditory ERPs. Results: There was no significant difference in P300 latencies between the SC-pretreatment group, SC-posttreatment group and control group (p>0.05). Mean interpeak latencies in SC-pretreatment group and SC-posttreatment group showed significant prolongation compared with the control group (p<0.05). Mean interpeak latencies in SC-posttreatment group were significantly decreased compared with SC-pretreatment group (p<0.05). Compared to controls, patients did not show significant difference in Stanford-Binet intelligence examination. Conclusion: This report suggests that interpeak latencies and amplitudes of P300 ERPs could be useful for detecting and monitoring cognitive impairment in SC patients. |
| Databáze: | MEDLINE |
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