| Autor: |
Romero I; Servicio de Analisis Clinicos e Inmunologia; UGC Laboratorio Clínico; Instituto de Investigación Biosanitaria ibs.GRANADA; Hospital Universitario Virgen de las Nieves; Granada, Spain., Garrido F; Servicio de Analisis Clinicos e Inmunologia; UGC Laboratorio Clínico; Instituto de Investigación Biosanitaria ibs.GRANADA; Hospital Universitario Virgen de las Nieves; Granada, Spain ; Departamento de Bioquímica; Biología Molecular e Inmunología III; Universidad de Granada; Granada, Spain., Garcia-Lora AM; Servicio de Analisis Clinicos e Inmunologia; UGC Laboratorio Clínico; Instituto de Investigación Biosanitaria ibs.GRANADA; Hospital Universitario Virgen de las Nieves; Granada, Spain. |
| Jazyk: |
angličtina |
| Zdroj: |
Oncoimmunology [Oncoimmunology] 2014 Jun 25; Vol. 3, pp. e29258. Date of Electronic Publication: 2014 Jun 25 (Print Publication: 2014). |
| DOI: |
10.4161/onci.29258 |
| Abstrakt: |
The mechanisms underlying cancer dormancy are poorly understood. We have developed a preclinical murine model in which immunosurveillance restrains spontaneous metastases in permanent dormancy. The model faithfully recapitulates human metastatic dormancy and may be useful to decipher the immune mechanisms constraining disease progression, thereby facilitating the development of novel immunotherapeutic approaches to control metastatic disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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