[Regulation of Yersinia pseudotuberculosis major porin expression in response to antibiotic stress].

Autor: Bystritskaia EP, Stenkova AM, Portniagina OIu, Rakin AV, Rasskazov VA, Isaeva MP
Jazyk: ruština
Zdroj: Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 2014 (2), pp. 17-21.
Abstrakt: The OmpF porin gene expression in Yersinia pseudotuberculosis in response to antibiotics of two different classes (kanamycin and nalidixic acid) was analyzed using quantitative PCR and a fluorescence reporter system. Both antibiotics downregulated the expression of the ompF gene. The nalidixic acid significantly reduced ompF expression, while kanamycin, for which porins are considered to be an alternative transport route, only slightly reduced the ompF level.
Databáze: MEDLINE