Sarcomatoid carcinoma of the lung: a model of resistance of chemotherapy.

Autor:	Ouziane I; Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco ; Jules Bordet Institute, Brussels, Belgium., Boutayeb S; Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco., Mrabti H; Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco., Lalya I; Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco., Rimani M; Department of Pathology, Hassan Loboratory, Rabat, Morocco., Errihani H; Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
Jazyk:	angličtina
Zdroj:	North American journal of medical sciences [N Am J Med Sci] 2014 Jul; Vol. 6 (7), pp. 342-5.
DOI:	10.4103/1947-2714.136920
Abstrakt:	Context: Lung tumors are very heterogeneous histological entities. Pulmonary sarcomatoid carcinoma is a subset of tumors characterized by specific histological features. Their poor prognosis compared to other lung tumors is due to limited responses to different types of chemotherapy. Case Report: WE REPORT TWO PATIENTS WITH SARCOMATOID TUMORS: A 53-year-old woman and a 46-year-old man who presented respiratory symptoms: Dyspnea, cough, associated with a deterioration of general condition. Conclusion: Pulmonary sarcomatoid carcinomas remained an unexplored entity, despite their poor prognosis. Based on these cases, we will discuss the histological and immunohistochemical features of these tumors, as well as report their responses to different chemotherapy regimens used in the course of treatment.
Databáze:	MEDLINE
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