Autor: |
Healey DS; National HIV Reference Laboratory, Fairfield Hospital, Victoria, Australia., Maskill WJ, Gust ID |
Jazyk: |
angličtina |
Zdroj: |
AIDS (London, England) [AIDS] 1989 May; Vol. 3 (5), pp. 301-4. |
DOI: |
10.1097/00002030-198905000-00009 |
Abstrakt: |
In a study of 23 subjects infected with HIV, a modified particle agglutination assay was used to detect anti-HIV-specific immunoglobulin M (IgM). The presence of anti-HIV IgM was demonstrated in every subject, becoming detectable 1-2 weeks after the onset of acute symptoms, and showing a variable duration of 1-5 weeks. Anti-HIV immunoglobulin G (IgG) developed 1-2 weeks after anti-HIV IgM. Particle agglutination detected the presence of specific antibody up to 7-10 days earlier than the Abbott recombinant or Genetic Systems enzyme immunoassays. In this study, all subjects with acute infection became clearly positive by Western blot within 3 months of the onset of acute symptoms. |
Databáze: |
MEDLINE |
Externí odkaz: |
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