| Autor: |
Groves NJ; Queensland Brain Institute, The University of Queensland, St. Lucia, Queensland 4072, Australia; email: t.burne@uq.edu.au., McGrath JJ, Burne TH |
| Jazyk: |
angličtina |
| Zdroj: |
Annual review of nutrition [Annu Rev Nutr] 2014; Vol. 34, pp. 117-41. |
| DOI: |
10.1146/annurev-nutr-071813-105557 |
| Abstrakt: |
Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin D has important roles in proliferation and differentiation, calcium signaling within the brain, and neurotrophic and neuroprotective actions; it may also alter neurotransmission and synaptic plasticity. Recent experimental studies highlight the impact that vitamin D deficiency has on brain function in health and disease. In addition, results from recent animal studies suggest that vitamin D deficiency during adulthood may exacerbate underlying brain disorders and/or worsen recovery from brain stressors. An increasing number of epidemiological studies indicate that vitamin D deficiency is associated with a wide range of neuropsychiatric disorders and neurodegenerative diseases. Vitamin D supplementation is readily available and affordable, and this review highlights the need for further research. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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