Perinatal autopsy evaluation of 2150 autopsies in the Çukurova region of Turkey.
| Autor: | Açikalin A; Department of Pathology, Çukurova University, Faculty of Medicine, ADANA, TURKEY., Bağir EK, Torun G, Ateş BT, Erdoğan S, Uğuz A, Ergın M, Büyükkurt S, Ozgünen FT, Tunali N, Gümürdülü D |
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| Jazyk: | angličtina |
| Zdroj: | Turk patoloji dergisi [Turk Patoloji Derg] 2014; Vol. 30 (3), pp. 189-94. |
| DOI: | 10.5146/tjpath.2014.01266 |
| Abstrakt: | Objective: We aimed to document the reasons of perinatal deaths in a large autopsy series performed in our institute, which is a reference center in the Çukurova region of Turkey. Material and Method: The study included 2150 autopsies performed between January 2000 and December 2012 at our institute. Diagnoses were categorized according to the detected pathologies; congenital malformations were detailed based on systems. Results: A pathology was detected in 1619 of 2150 (73.3%) autopsies. Congenital malformations were the most common diagnosis with 68.2%. Neural tube defects and central nervous system malformations were the most frequent system malformation in 28.8% of cases, followed by the urogenital system (11.4%) and musculoskeletal system (8.3%), respectively. Malformation syndromes including multisystem anomalies were defined in 109 cases (9.3%). Conclusion: Congenital malformations are the most common reason for perinatal deaths, with autopsy having an additive role to prenatal and genetic evaluations and providing foresight for planning a subsequent pregnancy. |
| Databáze: | MEDLINE |
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