Autor: |
Ullien D, Harmsma PJ, Abdulla SM, de Boer BM, Bosma D, Sudhölter EJ, de Smet LC, Jager WF |
Jazyk: |
angličtina |
Zdroj: |
Optics express [Opt Express] 2014 Jun 30; Vol. 22 (13), pp. 16585-94. |
DOI: |
10.1364/OE.22.016585 |
Abstrakt: |
Silicon optical microring resonators (MRRs) are sensitive devices that can be used for biosensing. We present a novel biosensing platform based on the application of polyelectrolyte (PE) layers on such MRRs. The top PE layer was covalently labeled with biotin to ensure binding sites for antibodies via a streptavidin-biotin binding scheme. Monitoring the shift in the microring resonance wavelength allows real-time, highly sensitive detection of the biomolecular interaction. |
Databáze: |
MEDLINE |
Externí odkaz: |
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