| Autor: |
Dos Banhos EF; Programa de Biologia Universidade Federal do Oeste do Pará Campus Rondon, SantarémPA Brazil., de Souza AQ; Laboratório de Genética Programa de Pós-Graduação em Biotecnologia e Recursos Naturais da Amazônia Escola de Ciências da Saúde Universidade do Estado do Amazonas ManausAM Brazil., de Andrade JC; Laboratório de Química Aplicada e Tecnologia Escola de Tecnologia Universidade do Estado do Amazonas ManausAM Brazil., de Souza AD; Departamento de Química Universidade Federal do Amazonas ManausAM Brazil., Koolen HH; Instituto de Química Universidade Estadual de Campinas CampinasSP Brazil., Albuquerque PM; Laboratório de Química Aplicada e Tecnologia Escola de Tecnologia Programa de Pós-Graduação em Biotecnologia e Recursos Naturais da Amazônia Universidade do Estado do Amazonas ManausAM Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2014 Apr 11; Vol. 45 (1), pp. 153-61. Date of Electronic Publication: 2014 Apr 11 (Print Publication: 2014). |
| DOI: |
10.1590/S1517-83822014005000027 |
| Abstrakt: |
Beneficial interactions between plants and microorganisms have been investigated under different ecological, physiological, biochemical, and genetic aspects. However, the systematic exploration of biomolecules with potential for biotechnological products from this interaction still is relatively scarce. Therefore, this study aimed the evaluation of the diversity and antimicrobial activity of the endophytic fungi obtained from roots, stems and leafs of Myrcia guianensis (Myrtaceae) from the Brazilian Amazon. 156 endophytic fungi were isolated and above 80% were identified by morphological examination as belonging to the genera Pestalotiopsis, Phomopsis, Aspergillus, Xylaria, Nectria, Penicillium and Fusarium. Fermented broth of those fungi were assayed for antimicrobial activity and four inhibited the growth of Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Penicillium avellaneum. As the strain named MgRe2.2.3B (Nectria haematococca) had shown the most promising results against those pathogenic strains, its fermented broth was fractioned and only its two low polar fractions demonstrated to be active. Both fractions exhibited a minimum bactericidal concentration of 50 μg.mL(-1) against S. aureus and a minimum fungicidal concentration of 100 μg.mL(-1) against P. avellaneum. These results demonstrate the diversity of fungal genera in M. guianensis and the potential of these endophytic fungi for the production of new antibiotics. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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