| Autor: |
Fei N; Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056, Basel, Switzerland. dennis.gillingham@unibas.ch., Häussinger D, Blümli S, Laventie BJ, Bizzini LD, Zimmermann K, Jenal U, Gillingham D |
| Jazyk: |
angličtina |
| Zdroj: |
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2014 Aug 11; Vol. 50 (62), pp. 8499-502. |
| DOI: |
10.1039/c4cc01919a |
| Abstrakt: |
We describe a simple method for the direct modification of nucleobases in cyclic purine dinucleotides, important signalling molecules in both prokaryotes and eukaryotes. The method tolerates all members of the cyclic dinucleotide family and could be used to modulate their function or introduce useful side-chains such as fluorophores and photo-crosslinking groups. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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