Compounds from marine-derived Verrucosispora sp. FIM06054 and their potential antitumour activities.

Autor: Yi-Lei N; a School of Pharmacy, Fujian Medical University , Fuzhou 350004 , P.R. China., Yun-Dan W, Chuan-Xi W, Ru L, Yang X, Dong-Sheng F, Hong J, Yun-Yang L
Jazyk: angličtina
Zdroj: Natural product research [Nat Prod Res] 2014; Vol. 28 (23), pp. 2134-9. Date of Electronic Publication: 2014 Jun 18.
DOI: 10.1080/14786419.2014.926350
Abstrakt: Strain FIM06054 was isolated from a marine sponge sample collected from the East China Sea and was characterised as a strain of Verrucosispora genus on the basis of its 16S rRNA gene sequence. One new compound, FW054-1 (1), together with a known aminofuran compound proximicin A (2), was isolated from the culture broth of Verrucosispora sp. FIM06054. Their structures were elucidated on the basis of spectral analysis. 1 and 2 showed antiproliferative activity against several human tumour cell lines.
Databáze: MEDLINE