Epidemiology of congenital hypothyroidism in Markazi Province, Iran.
| Autor: | Dorreh F; abriz University of Medical Sciences, National Public Health Management Center, Department of Community Medicine, Tabriz, Iran. E-ma-il: zenalali@gmail.com., Chaijan PY, Javaheri J, Zeinalzadeh AH |
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| Jazyk: | angličtina |
| Zdroj: | Journal of clinical research in pediatric endocrinology [J Clin Res Pediatr Endocrinol] 2014; Vol. 6 (2), pp. 105-10. |
| DOI: | 10.4274/Jcrpe.1287 |
| Abstrakt: | Objective: The aim of this study was to investigate the epidemiology of congenital hypothyroidism (CH) among newborns in Markazi Province, Iran. Methods: This cross-sectional study was conducted from 2006 to 2012. Blood samples were taken between 3 to 5 days after birth from the heel. Thyroid stimulating hormone (TSH) was tested using the enzyme-linked immunosorbent assay method and was employed as the screening test. Newborns with abnormal screening results (TSH >5 mIU/L) were re-examined. The data were analyzed using SPSS. Results: A total of 127 112 infants were screened. Of these, 51.2% were male and 48.8% were female. The coverage rate of the screening program was 100%. Of 6102 recalled subjects (re-call rate 4.8%), 414 cases with CH were detected, yielding a CH prevalence of 1:307 (female:male ratio 1:0.95). The prevalence of permanent and transient CH was 1:581 and 1:628, respectively. Conclusion: This study reveals that the prevalence of CH is higher compared to worldwide levels. Comprehensive and complementary studies for recognizing related risk factors should be a priority for health system research in this province. |
| Databáze: | MEDLINE |
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