The fetal safety of statins: a systematic review and meta-analysis.

Autor: Zarek J; The Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics, Hospital for Sick Children, Toronto ON., Koren G; The Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics, Hospital for Sick Children, Toronto ON.
Jazyk: angličtina
Zdroj: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC [J Obstet Gynaecol Can] 2014 Jun; Vol. 36 (6), pp. 506-509.
DOI: 10.1016/S1701-2163(15)30565-X
Abstrakt: Although an initial case series suggested that use of statins in pregnancy carried teratogenic risk, a recent meta-analysis of controlled observational studies has failed to corroborate this. A large number of potentially beneficial uses of statins in pregnant women have prompted a new evaluation of the risk-benefit ratio of these agents in pregnancy.
Databáze: MEDLINE