| Autor: |
Gur'yanova NN; Materia Medica Holding, Moscow, Russia, guryanovann@materiamedica.ru., Bugaeva LI, Lebedeva SA, Tekutova TV, Dugina YL, Petrov VI, Epshtein OI |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2014 May; Vol. 157 (1), pp. 37-41. Date of Electronic Publication: 2014 Jun 11. |
| DOI: |
10.1007/s10517-014-2486-0 |
| Abstrakt: |
We studied the efficiency of Dietressa on body weight reduction in C57Bl/6 male mice feeding standard high-fat ration (24%). After 5-month daily intragastric administration of Dietressa, body weight gain was the lowest in comparison with other groups and did not differ from that in mice receiving the reference substance sibutramine for 5 months. In contrast to sibutramine, Dietressa did not increase motor activity of animals in the open field test and produced no anorectic effect. The mean body weight gain per each 1000 kcal of consumed food in the group of animals receiving Dietressa was lower than in the control group and mice receiving sibutramine. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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