IL-23R gene polymorphism rs2201841 is associated with psoriatic arthritis.

Autor: Popadic S; Department of Dermatovenereology, School of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Dermatovenereology, Clinical Center of Serbia, Belgrade, Serbia., Ramic Z, Medenica Lj, Pravica V, Popadic D
Jazyk: angličtina
Zdroj: International journal of immunogenetics [Int J Immunogenet] 2014 Aug; Vol. 41 (4), pp. 335-7. Date of Electronic Publication: 2014 Jun 09.
DOI: 10.1111/iji.12127
Abstrakt: We examined rs2201841 within IL-23R gene in Serbian patients with psoriasis and healthy controls. G allele frequency was significantly increased in the group of patients with psoriatic arthritis compared with controls (0.481 vs 0.308). Carriage of G allele increases risk to develop psoriatic arthritis (P = 0.009, OR = 3.311, 95% CI 1.29-8.70).
(© 2014 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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