| Autor: |
Bazin GR, Gaspar MC, Silva NC, Mendes Cda C, Oliveira CP, Bastos LS, Cardoso CA |
| Jazyk: |
portugalština |
| Zdroj: |
Cadernos de saude publica [Cad Saude Publica] 2014 Apr; Vol. 30 (4), pp. 687-702. |
| DOI: |
10.1590/0102-311x00075413 |
| Abstrakt: |
This study aims to evaluate antiretroviral therapy in children and adolescents with AIDS. We selected 247 abstracts published from 1983 to 2013, collected from the PubMed and LILACS databases. Sixty-nine articles were selected. Attention to research in the pediatric age bracket in 30 years of the epidemic is explained by the age group's immunological characteristics, since AIDS progresses faster in children than in adults. Recent studies focus on the initiation of highly active antiretroviral therapy before the onset of symptoms. Early introduction of combination antiretroviral therapy has been implemented effectively and safely in populations with limited resources, leading to significantly improved survival. The current challenge is to manage a chronic disease with acute complications. New studies should focus on population specificities and identify the individual needs of pediatric patients. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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