Full-genome sequence of human betacoronavirus 2c jordan-n3/2012 after serial passage in Mammalian cells.
| Autor: | Frey KG; kenneth.frey@med.navy.mil gabriel.defang@med.navy.mil., Redden CL, Bishop-Lilly KA, Johnson R; National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA., Hensley LE; National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA., Raviprakash K; Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA., Luke T, Kochel T; Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA., Mokashi VP; Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland, USA., Defang GN; Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo, Egypt kenneth.frey@med.navy.mil gabriel.defang@med.navy.mil. |
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| Jazyk: | angličtina |
| Zdroj: | Genome announcements [Genome Announc] 2014 May 29; Vol. 2 (3). Date of Electronic Publication: 2014 May 29. |
| DOI: | 10.1128/genomeA.00324-14 |
| Abstrakt: | Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus. (Copyright © 2014 Frey et al.) |
| Databáze: | MEDLINE |
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